This book “The Protocol Book for Intensive Care” represents guidelines for the diagnosis and management of common medical emergencies seen in hospitals. It covers mostly cardiac problems but also includes respiratory, gastrointestinal, renal diseases and diabetes. It has the same objectives as the American Heart Association/American College of Cardiology’s Pocket Guidelines Updates compiled by the Special Task Forces of these organizations which are proving extremely useful for practicing physicians. The fifth edition has taken shape four years after the last, i.e. fourth edition which was published in 2014. Structurally, this edition is much alike its previous version; however, the content has been updated and revised in keeping with the recent developments in respective fields. Like the previous editions, the theme driving this one too is successful “complete management” of the patient. Afterall, there is no reason for a cardiologist to feel triumphant about a procedure performed by him/her, if the patient does not ultimately leave the hospital safe and sound because of a non-cardiac problem. The same of course applies to all disciplines of medicine.