This book explores the organizational and operational activities of real Positron Emission Tomography (PET) radiopharmaceutical manufacturing. Centered around the author’s professional experience, this book specifically explores: (1) the selection and preservation of operational and managerial personnel; (2) the alignment of production plans to consumer needs while still achieving financial goals; and (3) the positive and negative aspects of different operation management methods for direct and third-party production. The book offers a valuable reference for hospital managers, professionals and consultants interested or involved in developing a radiopharmaceutical facility/business or personalized medicine and special productions.