In this issue of Anesthesiology Clinics, guest editors Drs. Philipp Lirk and Kamen Vlassakov bring their considerable expertise to the topic of Orthopedic Anesthesiology. Top experts in the field cover key topics such as rebound pain, anesthesia for the general orthopedic patient, anesthesia and analgesia for the pediatric orthopedic patient, same-day major orthopedic surgery, hip fracture, and more.