Description
Plant Bioactives as Natural Panacea Against Age-induced Diseases: Nutraceuticals and Functional Lead Compounds for Drug Development presents comprehensive information on the complications of aging and the bioactive phytochemicals that in specific herbal formulations, including beverages, can mitigate them. The book extensively describes the current information on the role of plant bioactive components in delaying or preventing the aging process and associated complications, while also covering different strategies and scientific evidence of possible synergistic effects of these studies, enabling the formulation of more effective natural drugs to intervene in aging and associated events.
Extending lifespan/healthy aging has been the greatest wish of humans since
evolution. In the past few decades, significant advances have been seen in
the exploration of the aging process, its cellular biology, and biomarkers of
aging, which have provided specific targets that can be leveraged for possi-
ble aging interventions. There is no doubt that aging intervention is more
complicated than finding the cure for other diseases, since the aging process
is highly heterochronic. In addition, variations in theories explaining the
aging process, the strategies being exercised for an aging cure, or/and the
promotion of healthy aging are also highly diverse. However, intervening in
aging is always the next frontier in contemporary cure and will remain to be
of higher importance since aging not only affects the lifestyle of the indivi-
duals adversely but also brings dependency on others and costly medical
expenses.
Although the availability of advanced age care facilities has delayed the
development and progression of aging complications, still it is not feasible for
a large group of the population due to high costs. In addition, side effects asso-
ciated with these synthetic remedies have restricted their frequent and safe
use. In such a scenario, a sustainable cure with no/least side effects is the need
of the hour to combat the anticipated future burden of age-dependent
complications.
Bioactives from plants offer remarkable features in comparison with
traditional synthetic medicines which endow both advantages and chal-
lenges for drug discovery. Enormous scaffold diversity, structural com-
plexity, and higher numbers of H-bond acceptors/donors provide higher
molecular rigidity to these bioactives compared with synthetic compounds,
these characteristics are valuable in drug discovery tackling protein-pro-
tein interactions.
The present book is a comprehensive description of the antiaging poten-
tial of plant-derived bioactive compounds, naturally present in foods and
beverages, and it provides an update on aging intervention based on natural
compounds, which may be utilized in plant-based drug discovery against an
aging and associated complications. Written by a global team of experts, this
book may be an ideal resource for researchers in this area. This book has 22
chapters. Chapter 1 extends an expert opinion on aging principles and inter-
ventional perspectives. Chapters 2 and 22 discuss anti-aging strategies and
By Kanti Bhooshan Pandey CSIR-Central Salt & Marine Chemicals Research Institute, Bhavnagar, Gujarat, India Maitree Suttajit Thai Vegetarian Association, Changpuak, Chiang Mai, Thailand
