Foye’s Principles of Medicinal Chemistry 8th Edition (Foyes Eighth)

A groundbreaking book to offer a a comprehensive account of important reactions involving arynes  Modern Aryne Chemistry is the first book on the market to offer a conceptual framework to the reactions related to arynes. It also provides a systematic introduction to the cycloaddition reactions, insertion reactions and transition-metal-catalyzed transformations of arynes. The author, a noted expert on the topic, highlights a novel strategy for carbon-carbon and carbon-heteroatom bond construction using arynes. The book reveiws the recent use of aryne chemistry for the development of new multicomponent reactions. New advances in this area has shown rapid emergence of a new class of reactions classified under rearrangement reactions.  The author also includes information on aryne methods that have been employed for the synthesis of several natural products. The simplicity and sophistication of the synthetic strategy using arynes can serve as a springboard for organic chemists to explore new possibilities and imagine applications of the concept of arynes. This important book:

• Presents a one-of-kind comprehensive guide to arynes reactions
• Offers a proven approach to the synthesis of natural product and polymers
• Reviews the most recent developments in the carbon-carbon and carbon-heteroatom bond-forming reactions involving arynes

Written for organic, pharmaceutical, medicinal, natural products, and catalytic Chemists, Modern Aryne Chemistry offers a comprehensive review of the fundamentals of reactions related to arynes and the most recent developments in the field.