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This book presents an authoritative collection of HLA phenotyping and genotyping techniques to be used at the bench level and as a reference. It includes detailed methodologies, notes on the interpretation of tests, reference material, and appendices.

About the Author

Kam Man Hui, Ph.D., is Associate Professor and Head of the Laboratory of Molecular Immunology, Institute of Molecular and Cell Biology, National University of Singapore. Dr. Hui obtained his B.Sc. and M.Sc. degrees from Washington State University, and his Ph.D. in 1982 from Northwestern University Medical School in Chicago. After postdoctoral research training at the London Hospital Medical College and the National Institute for Medical Research in London, Dr. Hui took up his present appointment in 1987. During his postdoctoral years at the London Hospital Medical College, Dr. Hui was first introduced to research into the human major histocompatibility complex by the late Professor Hilliard Festenstein. Dr. Hui’s current research addresses the genetics and regulation of major histocompatibility genes in tumorigenesis. His laboratory is supported by the Singapore National Science and Technology Board. In 1990, jointly with Dr. Bidwell, Dr. Hui first described and patented the application of DNA heteroduplex technology to the HLADR- Dw system, and both colleagues continue to collaborate in the development of this and other related techniques.
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