There are many disorders of a lack of pigmentation in the skin, with different causations

and effects, of which vitiligo is only the best known; this comprehensive text from international

experts will enable clinicians to diagnose the full range of these conditions and suggest

the most effective management options for their patients.

Contents: Basic concepts of melanocyte biology * Approach to hypopigmentation *

Historical review of vitiligo * Epidemiology and classification of vitiligo * Pathophysiology

of vitiligo * Segmental vitiligo * Childhood versus post-childhood vitiligo * Pharmacological

therapy of vitiligo * Surgical treatment of vitiligo * Phototherapy and lasers in the treatment

of vitiligo * Emerging treatments for vitiligo * Tuberous sclerosis complex * Oculocutaneous

albinism * Hermansky-Pudlak syndrome, Chediak-Chigasi syndrome, and Griscelli

syndrome * Piebaldism * Waardenburg syndrome * Alezzandrini syndrome, Margolis

syndrome, Cross syndrome, and other rare genetic disorders * Mosaic hypopigmentation

• Skin disorders causing post-inflammatory hypopigmentation * Infectious and parasitic

causes of hypopigmentation * Melanoma leukoderma * Halo nevi * Drug-induced hypopigmentation

• Hypopigmentation from chemical and physical agents * Guttate hypomelanosis

and progressive hypomelanosis of the trunk (progressive macular hypomelanosis)