Lehne’s Pharmacology for Nursing Care 11th Edition

Description

Lehne’s Pharmacology for Nursing Care 11th Edition (Eleventh ed 11e) PDF

CONTENTS

UNIT I
INTRODUCTION
1 Orientation to Pharmacology 1
2 Application of Pharmacology in Nursing Practice 5
3 Drug Regulation, Development, Names, and
Information 14
UNIT II
BASIC PRINCIPLES OF PHARMACOLOGY
4 Pharmacokinetics 24
5 Pharmacodynamics 44
6 Drug Interactions 55
7 Adverse Drug Reactions and Medication Errors 63
8 Individual Variation in Drug Responses 74
9 Genetic and Genomic Considerations 79
10 Introduction to Immunomodulators 85
UNIT III
DRUG THERAPY ACROSS THE LIFE SPAN
11 Drug Therapy During Pregnancy and Breast-Feeding 90
12 Drug Therapy in Pediatric Patients 98
13 Drug Therapy in Older Adults 102
UNIT IV
PERIPHERAL NERVOUS SYSTEM DRUGS
SECTION 1 Introduction
14 Basic Principles of Neuropharmacology 108
15 Physiology of the Peripheral Nervous System 113
SECTION 2 Cholinergic Drugs
16 Muscarinic Agonists 126
17 Muscarinic Antagonists 131
18 Cholinesterase Inhibitors and Their Use in
Myasthenia Gravis 141
19 Drugs That Block Nicotinic Cholinergic
Transmission 148
SECTION 3 Adrenergic Drugs
20 Adrenergic Agonists 157
21 Adrenergic Antagonists 170
22 Indirect-Acting Antiadrenergic Agents 183
UNIT V
CENTRAL NERVOUS SYSTEM DRUGS
SECTION 4 Introduction
23 Introduction to Central Nervous System
Pharmacology 188
SECTION 5 Drugs for Neurodegenerative Disorders
24 Drugs for Parkinson Disease 191
25 Drugs for Alzheimer Disease 209
26 Drugs for Multiple Sclerosis 216
SECTION 6 Neurologic Drugs
27 Drugs for Seizure Disorders 234
28 Drugs for Muscle Spasm and Spasticit

SECTION 7 Drugs for Pain
29 Local Anesthetics 271
30 General Anesthetics 277
31 Opioid Analgesics, Opioid Antagonists, and
Nonopioid Centrally Acting Analgesics 286
32 Pain Management in Patients With Cancer 307
33 Drugs for Headache 323
SECTION 8 Psychotherapeutic Drugs
34 Antipsychotic Agents and Their Use in
Schizophrenia 334
35 Antidepressants 351
36 Drugs for Bipolar Disorder 372
37 Sedative-Hypnotic Drugs 380
38 Management of Anxiety Disorders 395
39 Central Nervous System Stimulants and Attention-
Deficit/Hyperactivity Disorder 402
SECTION 9 Substance Use Disorders
40 Substance Use Disorders I: Basic Considerations 412
41 Substance Use Disorders II: Alcohol 419
42 Substance Use Disorders III: Nicotine 430
43 Substance Use Disorders IV: Major Drugs of Abuse
Other Than Alcohol and Nicotine 438
UNIT VI
DRUGS THAT AFFECT FLUID AND ELECTROLYTE
BALANCE
44 Diuretics 454
45 Agents Affecting the Volume and Ion Content of
Body Fluids 466
UNIT VII
DRUGS THAT AFFECT THE HEART, BLOOD VESSELS,
AND BLOOD
46 Review of Hemodynamics 471
47 Drugs Acting on the Renin-Angiotensin-Aldosterone
System 477
48 Calcium Channel Blockers 492
49 Vasodilators 500
50 Drugs for Hypertension 505
51 Drugs for Heart Failure 523
52 Antidysrhythmic Drugs 540
53 Drugs That Help Normalize Cholesterol and
Triglyceride Levels 559
54 Drugs for Angina Pectoris 581
55 Anticoagulant, Antiplatelet, and Thrombolytic Drugs 594
56 Management of ST-Elevation Myocardial
Infarction 620
57 Drugs for Hemophilia 627
58 Drugs for Deficiency Anemias 635
59 Hematopoietic Agents 650
UNIT VIII
DRUGS FOR ENDOCRINE DISORDERS
60 Drugs for Diabetes Mellitus 660

61 Drugs for Thyroid Disorders 694
62 Drugs Related to Hypothalamic and Pituitary
Function 705
63 Drugs for Disorders of the Adrenal
Cortex 713
UNIT IX
WOMEN’S HEALTH
64 Estrogens and Progestins: Basic Pharmacology and
Noncontraceptive Applications 720
65 Birth Control 735
66 Drug Therapy for Infertility 749
67 Drugs That Affect Uterine Function 757
UNIT X
MEN’S HEALTH
68 Androgens 769
69 Drugs for Male Sexual Dysfunction and Benign
Prostatic Hyperplasia 778
UNIT XI
ANTIINFLAMMATORY, ANTIALLERGIC, AND
IMMUNOLOGIC DRUGS
70 Review of the Immune System 791
71 Childhood Immunization 802
72 Immunosuppressants 818
73 Antihistamines 828
74 Cyclooxygenase Inhibitors: Nonsteroidal
Antiinflammatory Drugs and Acetaminophen 836
75 Glucocorticoids in Nonendocrine Disorders 853
UNIT XII
DRUGS FOR BONE AND JOINT DISORDERS
76 Drug Therapy for Rheumatoid Arthritis 863
77 Drug Therapy for Gout 879
78 Drugs Affecting Calcium Levels and Bone
Mineralization 886
UNIT XIII
RESPIRATORY TRACT DRUGS
79 Drugs for Asthma and Chronic Obstructive
Pulmonary Disease 911
80 Drugs for Allergic Rhinitis, Cough, and
Colds 939
UNIT XIV
GASTROINTESTINAL DRUGS
81 Drugs for Peptic Ulcer Disease 947
82 Laxatives 960
83 Other Gastrointestinal Drugs 969
UNIT XV
NUTRITION AND COMPLEMENTARY THERAPY
84 Vitamins 983
85 Drugs for Weight Loss 996
86 Complementary and Alternative Therapy 1005
UNIT XVI
DRUGS FOR INFECTIOUS DISEASES
87 Basic Principles of Antimicrobial Therapy 1020
88 Drugs That Weaken the Bacterial Cell Wall I:
Penicillins 1034
89 Drugs That Weaken the Bacterial Cell Wall II:
Other Drugs 1043
90 Bacteriostatic Inhibitors of Protein Synthesis:
Tetracyclines, Macrolides, and Others 1053
91 Aminoglycosides: Bactericidal Inhibitors of Protein
Synthesis 1062
92 Sulfonamide Antibiotics and Trimethoprim 1069
93 Drug Therapy for Urinary Tract Infections 1078
94 Antimycobacterial Agents 1083
95 Miscellaneous Antibacterial Drugs 1100
96 Antifungal Agents 1106
97 Antiviral Agents I: Drugs for Non-HIV Viral
Infections 1117
98 Antiviral Agents II: Drugs for HIV Infection and
Related Opportunistic Infections 1141
99 Drug Therapy for Sexually Transmitted Infections 1177
100 Antiseptics and Disinfectants 1186
UNIT XVII
DRUGS FOR PARASITIC DISEASES
101 Anthelmintics 1193
102 Antiprotozoal Drugs I: Antimalarial Agents 1200
103 Antiprotozoal Drugs II: Miscellaneous Agents 1210
104 Ectoparasiticides 1215
UNIT XVIII
CANCER THERAPY
105 Basic Principles of Cancer Therapy 1221
106 Anticancer Drugs I: Cytotoxic Agents 1235
107 Anticancer Drugs II: Noncytotoxic Agents 1256
UNIT XIX
DRUGS FOR EYES, EARS, AND SKIN
108 Drugs for Eye Conditions and Diseases 1278
109 Drugs for Skin Conditions 1291
110 Drugs for Ear Conditions 1314
UNIT XX
TOXICOLOGY
111 Management of Poisoning 1321
112 Potential Weapons of Biologic, Radiologic,
and Chemical Terrorism 1326
APPENDIX A
Canadian Drug Information 1336
APPENDIX B
Prototype Drugs and Their Major Uses 1340