In this issue of Critical Care Nursing Clinics, guest editor and clinical nurse specialist Cynthia Benz brings her considerable expertise to the topic of Care for the Liver Failure Patient. Nurse involvement in chronic and fatal liver diseases requires interventions to improve symptom control, reduce inpatient care, prevent worsening of condition, and improve quality of life. In this issue, top experts focus on these nursing interventions for patients experiencing liver failure or the eventuality of liver failure.