The objective and endeavor of the manual remain to enhance knowledge and strengthen clinical practice in critical care. The manual broadly covers depths of scientific topics over all major organ systems and global current critical care practices. It is styled to serve as a ready bedside reference guide to all practitioners of critical care medicine. The chapters which are authored on wide evidence-based literature and knowledge, have been meticulously sifted, selected, and edited by experts in the discipline. The manual covers the full spectrum of critical care management and practice with contributions from experts in leading institutes across the country and abroad. The emphasis as always has been both on evidence and experience to make the manual more relevant and impactful to our young and upcoming critical care professionals